Natural Plaque Support for Dogs & Cats

Refrigeration after opening is recommended but not required if stored in a cool, dark place.

A 500 ml (16.9 oz) bottle typically lasts several months for an average-sized dog or cat, depending on the dosage and whether it is used in water or as a food topper

No. Plaque Guard™ is an excellent at-home support tool, but regular veterinary dental cleanings remain essential for complete oral health.

Consult your veterinarian first if your pet has specific health conditions, is on medication, has kidney or liver concerns, or has special dietary needs.

Dosage is based on your pet’s size. Always follow the guidelines on the bottle or product page. For first-time use, start with half the dose for one week so your pet can adjust.

Yes. It is designed for daily, long-term use in both dogs and cats when dosage instructions are followed.

You can use it two ways:

1. As a water additive: Mix 1 teaspoon (approx. 5 ml) per 1 quart (≈ 1 liter / 500–1000 ml depending on exact guidance) of fresh water. Change the water daily.
2. As a food topper: Add the recommended amount undiluted directly onto wet or dry food once or twice daily.

Plaque Guard™ is a natural dental water additive (also usable as a food topper) designed to help reduce plaque and tartar buildup, support healthier gums, and freshen breath in dogs and cats. It works with every sip or meal — no brushing required.

Is Plaque Guard™ safe for both dogs and cats? Yes. Plaque Guard™ is formulated to be safe for dogs and cats of all ages, sizes, and breeds when used as directed. There is a standard formula and a cat-specific formula that includes Wild Alaskan Salmon Oil for added omega-3 benefits and improved taste.

What are the main ingredients? Key ingredients include organic vegetable glycerin, papain (natural enzyme from papaya), zinc gluconate, pomegranate extract, wild blueberry extract, and other plant-based actives. All ingredients are human-grade or food-grade. The formula is free from artificial colors, flavors, harsh chemicals, alcohol, and xylitol.

Does Plaque Guard™ contain any ingredients that are toxic to pets? No. Unlike some competing products that use grape extracts (toxic to dogs and cats), Plaque Guard™ uses pet-safe antioxidants such as pomegranate and wild blueberry extracts.

Plaque Guard can be used as a water additive or a food topper. Simply follow the recommended dosage based on your pet’s size for safe, effective results.

Many pet owners notice fresher breath within 1–2 weeks. Visible improvements in plaque and tartar typically take longer and vary by the individual pet, diet, and starting oral health.

Independent studies referenced by the company show approximately 71.9% plaque reduction in dogs and 76.7% plaque reduction in cats when used as directed.

Plaque Guard™ is available directly through the official website (plaqueguard.com) and selected veterinary clinics. It is not sold in regular pet stores or big-box retailers. Or at Koa healthcare outside of the USA 

Reverse Osmosis Filtered Water

Ultra‑pure water that helps keep the formula clean, stable, and fresh—so every ingredient can do its job.

Organic Vegetable Glycerin

A gentle, plant-based ingredient that helps the formula mix smoothly, taste slightly sweet (no sugar), and deliver the good stuff evenly.

Organic Pomegranate Extract

A powerful antioxidant that helps support a healthier mouth by fighting the “bad guys” that can contribute to plaque and gum irritation.

Wild Blueberry Extract

Packed with antioxidants that help protect oral tissues and support overall wellness—while helping keep breath fresher.

Organic Chlorella

A nutrient-rich superfood with natural chlorophyll that supports freshness from the inside out and helps promote a clean, healthy system.

Organic Spirulina

Another superfood ingredient loaded with nutrients and antioxidants to support immune health and help your pet feel their best.

Natural Yucca Extract

Helps reduce odor (hello, fresher breath) and supports digestion—because a healthy gut can make a difference in overall freshness too.

Zinc Gluconate

A trusted mineral used in oral care to help slow down plaque-causing bacteria and support healthy gums.

Organic Papain Enzyme (from Papaya)

A gentle enzyme that helps break down protein-based buildup on teeth—without scraping or harsh abrasives.

Vitamin B2 (Riboflavin)

Supports healthy cells and tissues, including the gums and mouth—great for everyday maintenance.

Vitamin C (Ascorbic Acid)

An antioxidant that supports gum health and helps maintain strong, healthy tissues in the mouth.

Vitamin E (Tocopherol)

Helps protect oral tissues from oxidative stress and supports overall wellness (plus it helps keep the formula stable).

Organic Clove Extract

Traditionally used in oral care—supports a cleaner mouth and fresher breath with natural plant power.

Organic Cinnamon Extract

Naturally supports a balanced oral environment and helps keep breath smelling better.

Liquid Chlorophyll

Nature’s “deodorizer”—helps neutralize odor and supports fresher breath from within.

Natural Xanthan Gum

A plant-based stabilizer that keeps everything blended properly and helps the solution stay consistent.

Sorbic Acid + Potassium Sorbate

Food-grade preservatives that help keep Plaque Guard fresh and safe by preventing spoilage—without harsh chemicals.

Wild Salmon Oil (Cat Formula Only)

Omega‑3s (EPA & DHA) to support gums, skin, and coat—plus it makes the cat formula extra tasty.

Simple ingredients. Real results.
Plaque Guard is a daily dental water additive made with carefully chosen, human‑grade ingredients to help support cleaner teeth, healthier gums, and fresher breath—just by adding it to your pet’s water.Plus: pH-balanced for maximum effect.
Plaque Guard is pH-balanced to help the formula work at its best in your pet’s water bowl—supporting ingredient stability, comfort, and consistent daily use.

Yes. It is manufactured in-house at the company’s facility in Arthur, Ontario, Canada.

 VOHC certification requires clinical trials on laboratory-housed animals. With more than 37,000 dogs already used in laboratory testing each year in the U.S., we refuse to add to that number. Plaque Guard is formulated with human-grade ingredients backed by decades of established scientific research. We protect your pet’s teeth without ever compromising another animal’s freedom or wellbeing.

When used as directed, side effects are rare. As with any new product, introduce it gradually. Discontinue use and consult your veterinarian if you notice anything unusual.

Yes. Plaque Guard is compatible with pet water fountains. Add the measured dose when you fill or refresh the fountain as you normally would. Fountains with activated carbon filters may reduce the concentration of active ingredients over time, so you may see better results by cleaning and refreshing the fountain daily as recommended.

Absolutely. Senior pets often benefit most from a gentle, passive dental care solution because they may be less tolerant of brushing and are more likely to have existing gum sensitivity. The plant-based formula is gentle and safe for older animals of all breeds and sizes.

Plaque Guard is designed to support ongoing dental health and reduce new plaque buildup, but it is not a treatment for existing dental disease, periodontal infections, or tooth decay. If your pet has been diagnosed with active dental disease, your veterinarian should address that first. Once any acute issues are resolved, Plaque Guard is an excellent preventative tool to help maintain the results and keep plaque from returning.

Papain enzyme is a natural protein-digesting enzyme from papaya that helps break down the plaque-forming proteins that stick to your pet's teeth. Zinc gluconate supports gum health and inhibits bacterial growth. Organic pomegranate and wild blueberry extracts are rich in antioxidants that reduce gum inflammation. Yucca extract helps with odor control and supports a healthy oral environment. Organic vegetable glycerin acts as a natural humectant that helps prevent plaque from adhering to tooth surfaces.

Yes. Plaque Guard is recommended by hundreds of veterinarians across the USA, Canada, and UK. It is trusted by professionals because it is made with clinically studied ingredients and has undergone independent clinical trials that produced measurable results. Many vets appreciate having a practical, stress-free solution to recommend to pet owners who struggle with at-home brushing routines.

Brushing is the gold standard of pet dental care, but most pets resist it and most owners find it difficult to do consistently. An inconsistent brushing routine provides far less benefit than a daily passive routine that never gets skipped. Plaque Guard works every single day with no effort and no struggle, which means your pet gets consistent protection. For households that do brush regularly, Plaque Guard also serves as a valuable complement between sessions.

When you compare the cost of Plaque Guard to the alternative, the math tells a clear story. A professional veterinary dental cleaning can cost anywhere from $500 to $2,000 or more, and most pets need them more frequently when at-home dental care is neglected. Plaque Guard costs as little as $0.50 per day for a 15 lb dog — significantly less than $200 per year. You can use the Pet Savings Calculator on our website to see the cost comparison based on your pet's size. For the majority of pet owners, Plaque Guard pays for itself many times over.

Plaque Guard dramatically reduces plaque buildup and supports better gum health, which means many pet owners find their vets recommend less frequent professional cleanings. However, it is not a substitute for periodic veterinary dental exams. Your vet may still recommend annual or biannual checkups to monitor overall oral health, particularly for older pets or breeds prone to dental issues. Think of Plaque Guard as the best defense you can provide between those visits.

This is a fair question. The upfront price of $73 with free shipping is often compared to dental chews or flavored toothpaste. What separates Plaque Guard is that it is backed by independent clinical trials showing a 70% reduction in plaque within 30 days — most budget alternatives carry no clinical evidence whatsoever. You are paying for a formula that works at a molecular level, made with human-grade ingredients, and trusted by veterinary professionals. When weighed against the cost of the vet visits it helps prevent, the value is substantial.

Yes. Plaque Guard is safe for multi-pet households. If your dogs and cats share a water bowl, dose based on the weight of the smallest pet to ensure none of them receive more than the recommended amount. Ideally, each pet has their own bowl so you can control dosing precisely, but shared-bowl use is safe whenyou follow the label directions carefully.

Plaque Guard is formulated to be low-odor and palatable. The overwhelming majority of pets accept it without hesitation because the formula is very mild at the diluted concentration used in the water bowl. If your pet seems reluctant at first, start with a slightly lower dose for the first few days and gradually work up to the full amount to allow them to adjust.

We stand behind the results that Plaque Guard delivers. If you have questions about our return or satisfaction policy, please visit our website or reach out to our customer support team directly. We want every pet owner who tries Plaque Guard to feel confident in their purchase.

Both Plaque Guard and Healthymouth use water additive technology with overlapping core ingredients. The key differences come down to formulation philosophy, ingredient sourcing, and availability. Plaque Guard uses strictly human-grade, plant-based ingredients with no artificial additives — a standard that matters to many pet owners today. Our formula has been developed with veterinary input and validated through independent clinical trials showing 70% plaque reduction in 30 days. We also maintain consistent availability across the USA, Canada, and UK, so customers can count on their supply arriving when expected.

The most common reason Plaque Guard does not produce visible results is inconsistent daily use. The formula works cumulatively — missing days resets some of the progress. If you have been using it consistently for 30 days and are not seeing improvement, review your dosing to ensure you are adding the right amount based on your pet's current weight. If your pet has significant existing tartar or gum disease, that underlying condition may need to be addressed by a vet first before the additive can work effectively as a maintenance tool. Reach out to our team — we are happy to help troubleshoot and make sure you are getting the most out of your purchase.